Polynucleotides (PN / PDRN) for cosmetologists and doctors

Polynucleotides (PN) are highly purified DNA fragments from salmonid fish (rainbow trout) tissue, 95% identical to human DNA. Injected intradermally, they activate adenosine A2A receptors, stimulate fibroblasts and the synthesis of collagen and elastin, improve microcirculation and reduce inflammation. The result is denser, hydrated, more even skin with a long-lasting regenerative effect — not just a short-term increase in volume.

Skin quality improvement and preventive anti-ageing therapy; periorbital area; acne and post-acne scars, stretch marks; recovery after laser, peels and microneedling; skin preparation before and after other injectable procedures; neck, décolleté, hands.

Standard course — 3–4 sessions at 2–3-week intervals, maintenance every 4–6 months. Administration — intradermal papular, linear or nappage technique with a 30–32G needle or cannula. Preparations with patented PAIN-RELIEF technology (pH 7.6–7.8, mannitol-free) make the procedure more comfortable and reduce the risk of side effects. Detailed protocols are provided to registered clients.

All polynucleotide preparations are CE-marked medical devices registered with the Latvian State Agency of Medicines (ZVA / LATMED). Glowinn supplies original CE-marked preparations: traceable batches, correct storage and transport, stock in Riga and documentation for every batch.

Products are available only to licensed medical professionals and qualified cosmetologists. Register, and after document verification your account will show prices and allow ordering with delivery by Omniva / SmartPosti in Latvia, Lithuania and Estonia, or by courier to Finland and Scandinavia. Questions — WhatsApp or info@glowinn.lv.

PDRN (polydeoxyribonucleotides) and PN (polynucleotides) are fractions of different length from the same raw material — purified salmon DNA. PN consists of longer chains that form a viscoelastic matrix in the skin and act as a biostimulator: density, firmness, skin quality. PDRN consists of shorter chains with a more pronounced effect on cell receptors, so it is more often used for regeneration and soothing after laser, peeling and microneedling procedures. In the catalogue PDRN appears in the PDRN 0.5% + HA 0.2% skin booster, in the Synerlift and Lumi Na+ju cocktails, and in serums and creams for home care. Both fractions can be combined in one protocol.

Periorbital skin is thinner, drier and more sensitive than the rest of the face, so it has a preparation of its own — PN 20 mg/ml for the eye area (HP VITARAN i, 2×1 ml). Indications: dark circles, thin and dehydrated skin, fine expression lines, loss of firmness under the eyes. Administration is superficial, with a fine needle or cannula; the course and technique follow the general polynucleotide protocol, with details available to registered clients.